LhARA Radiobiology Meeting: 20Aug26; 14:00 BST

ZOOM: ​https://imperial-ac-uk.zoom.us/j/98220889714?pwd=SM90vOF7BKSXoU3mD9q7OwBQo4IVB3.1

• Planning Document: ​https://docs.google.com/document/d/1OTARVtxhLRu02S6CLdRDB2QlGvCqDfZ3aWBifjIFs_Q/edit?tab=t.0

• Trello: ​https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar

Meeting Agenda

1. Beamline Simulation
   • Josie: Characterisation of ELI and SCAPA sources
   • Josie: Simulations of a dipole at SCAPA

2. Instrumentation
   • Fast Electrons
     • Richard H.: Findings since last meeting
   • RCF
     • Update from NPL
     • Mark has found some EBT4 delaminated: ​https://www.ashland.com/industries/medical/radiotherapy-films/ebt4
   • Air Scintillation
     • Colin/Narendar: Planning to meet to discuss the feasibility of the implementation at SCAPA and the timeframe

3. BioPrep
   • Notes from meeting with Alexander Mullen
     • Vertical beam needed?

4. SCAPA
   • Updates

5. Review Trello: ​https://trello.com/invite/b/67587c515b0c69656ee78b48/ATTIe86f94b24e3e5884e4cb87e5ed3b89ab64321B83/poplar

6. DoNM
   • 03/09/26

7. AoB

Summary of actions required

In-Beam Diagnostics

• Unassigned: Acquire a glass sheet
• Unassigned: Get a new RCF batch and calibrate
• TP: Testing delaminating EBT3
• PH: Obtain transparent fibre or an alternative method for light transport
• PH: Obtain a lens for hollow fibre tests
• CD: Simulate energy deposited in transport fibres
• KL, CD, JMcG, PH: Design a system to make full scifi prototypes
• KL, CD, JMcG, PH: Make a full scifi prototype
• KL, CD: Send clear fibre to SCAPA before 16th August (Contact Ewan or Colin since Robbie is USA)
• KL, CD, JMcG, PH: Discuss visit to Birmingham to test SciFi
• RW, CD: Study the correlation between laser diagnostics and mean dose
• Unassigned: Investigate how a phosphor sheet could be incorporated into the design of the cell dish
• CW: Investigate the feasibility of ICTs for our beamline
• MH: Investigate LET detector
• CW: Ask Narender about air fluorescence implementation
• JMcG: Investigate using IF as a dosimeter

Bio Next Steps

• EM, CD, JMcG: Write up technical summary of Phase 2
• EM: Write up a biology plan for a 2 PMQ setup
• Unassigned: Obtain an inverted microscope
• Unassigned: Obtain multi-chamber haemocytometers (Might be able to use Birmingham's)
• Unassigned: Obtain a thermostat for the incubator
• EM: Run controls to examine how long the cells can survive vertically
• JMcG: Plan a test of vertical cell survival using Emma/Jason's HeLa cell line and Marie's cell line
• JMcG: Produce a HeLa colony that can survive on Mylar

Beamline Modelling

• Unassigned: Investigate how to improve the beamline beyond CV=8%
• CD: Examine energy spectra variation
• RW, CD: Source characterisation

Alternate Beamlines

• JMcG: Simulate BELLA
• JMcG: Simulate ELI

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